The Times of India

How did Sandro Botticelli's muse, the 'most beautiful woman' of Italian Renaissance paintings, die? New research claims to solve a five-century-old death mystery

A new study challenges the long-held belief about Simonetta Vespucci's death. Researchers propose she died from a pituitary tumor, not tuberculosis. Facial recognition algorithms analyzed portraits for hormonal changes. Historical letters described her final symptoms and collapse during a ball. This evidence suggests a rapid tumor complication caused her untimely demise.