Phys.org

Light-emitting nanoparticles help ultrasound direct gene editing to selected mouse brain regions

Scientists can now edit genes in precise locations deep in the brain and body without the use of invasive surgery or implants, thanks to new work from researchers at the Wu Tsai Neurosciences Institute. The team demonstrated its technique, which uses a combination of ultrasound, light-emitting nanoparticles and photo-controllable gene-editing proteins, by successfully altering genes in mouse brains at selected locations.