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Science/Tech News

Phys.org

Science/Tech / Phys.org

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Chemists unlock Appel fluorination with potassium fluoride

Alcohols are among the most abundant building blocks in chemistry. Fluorinated compounds, meanwhile, are essential for many modern medicines, crop protection products and advanced materials. Converting one into the other, however, has traditionally relied on toxic, thermally unstable reagents such as DAST (diethylaminosulfur trifluoride) that make large-scale manufacturing operationally demanding.

31 Jul 2026 8:50 pm